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David L. Callender, MD; Robert A. Frankenthaler, MD; Mario A. Luna, MD; Sang Sook Lee, MD; Helmuth Goepfert, MD

Arch Otolaryngol Head Neck Surg. 1992;118(5):472-476.

Abstract
• Of 29 patients, aged 3 to 16 years, with nonvasoformative salivary gland tumors, 21 had malignant tumors. Mucoepidermoid carcinoma was the most common; adenocarcinoma, adenoid cystic carcinoma, and acinic cell carcinoma were equally represented. Pleomorphic adenoma was the exclusive benign lesion, occurring in eight patients. Mean follow-up for patients with malignant lesions was 13.6 years (minimum, 3.5 years). Absolute 2- and 5-year survival rates were 100% and 90%, respectively. Mean follow-up for benign lesions was 15.9 years; none recurred. Superficial or total parotidectomy is the treatment of choice for malignant parotid neoplasms. Benign parotid lesions are adequately controlled with parotidectomy based on extent of disease. Facial nerve sacrifice can often be avoided. We advocate postoperative radiotherapy for high-grade lesions or those with adverse prognostic factors, such as soft-tissue extension and perineural invasion.

(Arch Otolaryngol Head Neck Surg. 1992;118:472-476)

Author Affiliations
From the Departments of Head and Neck Surgery (Drs Callender, Frankenthaler, and Goepfert) and Pathology (Drs Luna and Lee), The University of Texas M. D. Anderson Cancer Center, Houston.

Footnotes
Accepted for publication December 9, 1991.

Presented at the 33rd annual meeting of the American Society for Head and Neck Surgery, Waikaloa, Hawaii, May 9, 1991.

Reprint requests to the Department of Head and Neck Surgery, Box 69, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 (Dr Callender).

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