This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Histologic Evaluation

Henry T. Hoffman, MD; Nancy Harrison, MD; Michael J. Sullivan, MD; K. Thomas Robbins, MD; Marion Ridley, MD; Shan R. Baker, MD

Arch Otolaryngol Head Neck Surg. 1991;117(8):917-925.

Abstract
• To our knowledge, a histologic evaluation of bone healing after mandible reconstruction with vascularized human bone grafts has not been previously reported. Serial sections through both the decalcified graft and the junction between mandible and graft were evaluated in four patients who required surgical removal of their reconstructed mandibles. A failed scapular bone graft that had been wrapped within a pectoralis major myocutaneous flap for salvage following pedicle thrombosis showed markedly resorbed but viable bone with a fibrous union to the native mandible. Viable vascularized grafts without evidence of ongoing resorption characterized an iliac osteocutaneous bone graft and two scapula osteocutaneous grafts that healed with continuity of healthy bone between graft and mandible. Observations from the evaluation of these specimens are made regarding bone circulation, bone union, and bone graft survival as they occur clinically. Implications regarding the techniques of bone plating and indications for use of vascularized bone in mandible reconstruction are discussed.

(Arch Otolaryngol Head Neck Surg. 1991;117:917-925)

Author Affiliations
From the Department of Surgery, Division of Otolaryngology, University of California, San Diego, Medical Center and the Veterans Affairs Medical Center, San Diego (Drs Hoffman and Robbins); the Department of Pathology, University of California, San Diego, Medical Center (Dr Harrison); the Department of Otolaryngology, University of Michigan, Ann Arbor (Drs Sullivan and Baker); and the Department of Surgery, Division of Otolaryngology, University of South Florida, Tampa (Dr Ridley). Dr Hoffman is now with the Department of Otolaryngology—Head and Neck Surgery, The University of Iowa Hospitals and Clinics, Iowa City.

Footnotes
Accepted for publication provisionally November 26, 1990; final acceptance after revision March 5, 1991.

Reprint requests to Department of Otolaryngology—Head and Neck Surgery, The University of Iowa Hospitals and Clinics, Iowa City, IA 52242 (Dr Hoffman).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Microvascular Free-Flap Reconstruction in the Head and Neck
Futran and Alsarraf
JAMA 2000;284:1761-1763.
FULL TEXT  

Otolaryngology--Head and Neck Surgery
Bailey
JAMA 1992;268:395-397.
ABSTRACT