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Robert J. Baatenburg de Jong, MD, PhD; Robert J. Rongen, MD, PhD; Carel D. A. Verwoerd, MD, PhD; Hans van Overhagen, MD; Johan S. Laméris, MD, PhD; Paul Knegt, MD, PhD

Arch Otolaryngol Head Neck Surg. 1991;117(4):402-404.

Abstract
• The assessment of nodal involvement in patients with squamous cell carcinoma of the head and neck is still a major diagnostic problem. Although the sensitivity of imaging techniques for detection of neck nodes is gradually improving, the specificity for metastases remains low. Cytologic examination could, theoretically, supply additive information. Computed tomographic—and magnetic resonance—guided aspiration techniques have been described, but these were not efficacious and laborious. In 1984, we developed a technique for ultrasound-guided (UG) fine-needle aspiration biopsy (FNAB). This technique is described herein, and the value of UGFNAB is compared with conventional FNAB. All statistical characteristics of UGFNAB appeared to be superior to conventional FNAB (sensitivity, 98% vs 88%; specificity, 95% vs 82%; positive predictive value, 98% vs 93%; negative predictive value, 95% vs 74%; and accuracy, 97% vs 87%). Furthermore, UGFNAB was characterized by less nondiagnostic aspirations. It is concluded that UGFNAB is a reliable technique for differentiation between benign nodes and cervical lymph node metastases and it may, therefore, contribute to a more accurate assessment of the neck in squamous cell carcinoma of the head and neck.

(Arch Otolaryngol Head Neck Surg. 1991;117:402-404)

Author Affiliations
From the Departments of Otorhinolaryngology (Drs Baatenburg de Jong, Verwoerd, and Knegt) and Radiology (Drs van Overhagen and Laméris), Dijkzigt University Hospital, Rotterdam; and Department of Radiology, Canisius-Wilhelmina Hospital, Nijmegen (Dr Rongen), the Netherlands.

Footnotes
Accepted for publication December 20, 1990.

Reprint requests to Department of Otorhinolaryngology, Dijkzigt University Hospital, Dr. Molenwaterplein 40, 3015GD Rotterdam, the Netherlands (Dr Baatenburg de Jong).

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