This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Clinical and Pathologic Review

William J. Kane, MD; Thomas V. McCaffrey, MD, PhD; Kerry D. Olsen, MD; Jean E. Lewis, MD

Arch Otolaryngol Head Neck Surg. 1991;117(3):307-315.

Abstract
• One hundred ninety-four patients with primary malignant tumors of the parotid gland who underwent surgery at the Mayo Clinic (1970 through 1987) are reviewed. Survival patterns were analyzed using the Kaplan-Meier product-limit method that separated histologic results into three significantly different groups. Survival rate was highest for patients with acinic cell, adenoid cystic, and low-grade mucoepidermoid carcinomas; intermediate for patients with high-grade mucoepidermoid carcinomas; and lowest for the remaining six histologic types encountered. Cox multiple linear regression was used to identify patient and tumor characteristics with greatest prognostic significance. In order of decreasing strength, regional metastatic involvement, pain, male gender, grade, stage, and advancing age all demonstrated independent prognostic significance. Fifty-three percent of patients requiring facial nerve sacrifice were asymptomatic at presentation. A high positive correlation was observed between advancing grade and stage.

(Arch Otolaryngol Head Neck Surg. 1991;117:307-315)

Author Affiliations
From the Department of Otorhinolaryngology (Drs Kane, McCaffrey, and Olsen) and the Division of Surgical Pathology (Dr Lewis), Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Accepted for publication October 15, 1990.

Presented at the Combined Otological Spring Meeting, Palm Beach, Fla, May 1, 1990.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr McCaffrey).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Mucoepidermoid Carcinoma of the Parotid Gland: The Mayo Clinic Experience
Boahene et al.
Arch Otolaryngol Head Neck Surg 2004;130:849-856.
ABSTRACT | FULL TEXT  

Nodal Metastasis in Major Salivary Gland Cancer: Predictive Factors and Effects on Survival
Bhattacharyya and Fried
Arch Otolaryngol Head Neck Surg 2002;128:904-908.
ABSTRACT | FULL TEXT  

Limitations of Magnetic Resonance Imaging in the Evaluation of Perineural Tumor Spread Causing Facial Nerve Paralysis
Jungehuelsing et al.
Arch Otolaryngol Head Neck Surg 2000;126:506-510.
ABSTRACT | FULL TEXT  

Pediatric Parotid Masses
Orvidas et al.
Arch Otolaryngol Head Neck Surg 2000;126:177-184.
ABSTRACT | FULL TEXT  

Acinic Cell Carcinoma of Salivary Glands: Prognostic Relevance of DNA Flow Cytometry and Nucleolar Organizer Regions
Timon et al.
Arch Otolaryngol Head Neck Surg 1994;120:727-733.
ABSTRACT  

Primary Squamous Cell Carcinoma of the Parotid Gland
Gaughan et al.
Arch Otolaryngol Head Neck Surg 1992;118:798-801.
ABSTRACT  

Prognostic Variables in Parotid Gland Cancer
Frankenthaler et al.
Arch Otolaryngol Head Neck Surg 1991;117:1251-1256.
ABSTRACT