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Toshimitsu Kobayashi, MD; Nobuyuki Shiga, MD; Koji Hozawa, MD; Sho Hashimoto, MD; Tomonori Takasaka, MD

Arch Otolaryngol Head Neck Surg. 1991;117(11):1292-1295.

Abstract
• Recording of the cochlear potentials was successfully performed during experimental labyrinthectomy in the guinea pig and in three patients with acoustic neuromas during translabyrinthine removal of the tumors. In the guinea pig, complete interruption of the duct of the lateral semicircular canal including the endolymphatic canal caused little change in the endocochlear DC potential of the first cochlear turn and input-output function curve of the N₁ component of the compound action potential elicited by 8-kHz tone bursts. Further drilling of the vestibular labyrinth in the guinea pig caused decline of these potentials when the vestibule was opened. In patients with acoustic neuromas, the interruption of the duct of the lateral semicircular canal hardly altered the N₁ input-output function curve and N₁ input-latency function curve during the 1-hour observation period. Consistent preservation of cochlear function even after interruption of lateral semicircular canals suggests the possibility of partial surgical labyrinthectomy with preservation of hearing for lesions involving semicircular canals.

(Arch Otolaryngol Head Neck Surg. 1991;117:1292-1295)

Author Affiliations
From the Department of Otolaryngology, Tohoku University School of Medicine, Sendai, Japan.

Footnotes
Accepted for publication March 22, 1991.

Presented in part at the 36th Annual Meeting of the Japan Society of Ear Research, Kofu, Japan, February 10, 1989; and at the 26th Workshop on Inner Ear Biology, Paris, France, September 6, 1989.

Reprint requests to Department of Otolaryngology, Tohoku University School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai 980, Japan (Dr Kobayashi).

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