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The Pathologic and Thermal Effects of Gold Vapor Laser Photodynamic Therapy on the LarynxExperimental Study
Allan L. Abramson, MD;
Adam S. Levy;
Larry S. Hirschfield, MD
Arch Otolaryngol Head Neck Surg. 1990;116(6):687-691.
Abstract
A gold vapor laser, which emits short pulses of light at a wavelength of 628 nm, was used to deliver varying amounts of energy (30 to 120 J cm2) to the presensitized (dihematoporphyrin ether) canine larynx. Between 30 and 60 J/cm2, the larynx appeared normal, and when 70 to 100 J/cm2 was applied, only mild edema and erythema were seen. Simultaneously, a thermocouple probe was used and a 0.4°C to 1.5°C temperature rise found. Thus, the gold vapor laser seems capable of achieving the therapeutic photosensitizing effect without causing significant laryngeal edema or thermal activity.
(Arch Otolaryngol Head Neck Surg. 1990;116:687-691)
Author Affiliations
From the Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, New Hyde Park, NY.
Footnotes
Accepted for publication February 6, 1990.
Reprint requests to Department of Otolaryngology and Communicative Disorders, Long Island Jewish Medical Center, New Hyde Park, NY 11042 (Dr Abramson).
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