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Gail J. Anderson, MD; Lawrence W. C. Tom, MD; Richard B. Womer, MD; Steven D. Handler, MD; Ralph F. Wetmore, MD; William P. Potsic, MD

Arch Otolaryngol Head Neck Surg. 1990;116(4):428-431.

Abstract
• Rhabdomyosarcoma is the most common soft-tissue sarcoma in infants and children, with the head and neck being the most frequent site of involvement. Treatment for this neoplasm has undergone many changes, with a much improved prognosis using a combination of surgery, radiation therapy, and chemotherapy. This retrospective analysis presents the management and outcome of 60 children (aged 3 months to 18 years) with rhabdomyosarcoma of the head and neck evaluated at the Children's Hospital of Philadelphia (Pa) between 1970 and 1987. The overall death rate for all head and neck sites decreased from 50% in 1970 to 1979 to 23% in 1980 to 1987, reflecting the improved management protocol.

(Arch Otolaryngol Head Neck Surg. 1990;116:428-431)

Author Affiliations
From the Divisions of Otolaryngology (Drs Anderson, Tom, Handler, Wetmore, and Potsic) and Oncology (Dr Womer), Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine.

Footnotes
Accepted for publication September 19, 1989.

Read before the American Society of Pediatric Otolaryngology, San Diego, Calif, May 19, 1989.

Reprint requests to the Division of Otolaryngology, Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104 (Dr Tom).

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