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A Refined Model for Skin Flap Research

Todd J. Freeman, MD; James I. Cohen, MD, PhD

Arch Otolaryngol Head Neck Surg. 1990;116(2):189-190.

Abstract
• The rat has long been used as an experimental model for obtaining preliminary data in skin flap research. Unfortunately, there has been a great deal of inconsistency both in the experimental design of the skin flaps used in this animal model and in their inherent survival pattern. We have developed a ventral "L" flap based on clear anatomic landmarks that offers a number of advantages over previously described rat skin flaps including a more consistent survival pattern. This flap was elevated in 23 rats, resulting in an average necrosis of 16.7% ± 7.6% 7 days postoperatively. Our article outlines the details of this flap's design and its use. The ventral L flap offers a refined tool for skin flap research in the rat animal model.

(Arch Otolaryngol Head Neck Surg. 1990;116:189-190)

Author Affiliations
From the Department of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis (Dr Freeman); and Department of Otolaryngology—Head and Neck Surgery, Oregon Health Sciences University, Portland (Dr Cohen).

Footnotes
Accepted for publication July 3, 1989.

Presented at the Spring meeting of the American Academy of Facial Plastic and Reconstructive Surgery, Palm Springs, Fla, April 30, 1988.

Reprints not available.

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