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The Efficacy of Oral Steroids in the Treatment of Persistent Otitis Media With Effusion
Ludwig Podoshin, MD;
Milo Fradis, MD;
Yacov Ben-David, MD;
David Faraggi, PhD
Arch Otolaryngol Head Neck Surg. 1990;116(12):1404-1406.
Abstract
One hundred thirty-six children with otitis media with effusion of at least 2 months' duration were investigated in a strict, double-blind, randomized prospective study to evaluate the efficacy of oral steroids in the treatment of this disease. The results of our study showed a significant complete and partial recovery from otitis media with effusion in the group treated by a combination of antibiotics (amoxicillin) and oral steroids (prednisone), compared with an amoxicillin-treated group and a placebo-treated group. We believe that this treatment mostly benefits children aged 4 to 10 years without oversized adenoids. The findings of our study imply that a combined course of antibiotics and oral steroids deserves its place as a routine conservative trial before surgery.
(Arch Otolaryngol Head Neck Surg. 1990;116:1404-1406)
Author Affiliations
From the Department of Otolaryngology, Bnai Zion Medical Center (Drs Podoshin, Fradis, and Ben-David), the Department of Medicine, Technion-Israel Institute of Technology (Drs Podoshin, Fradis, and Ben-David), and the Department of Statistics, Haifa University (Dr Faraggi), Haifa, Israel.
Footnotes
Accepted for publication June 19, 1990.
Presented in part at the Conference on the Eustachian Tube and Middle Ear Diseases, Geneva, Switzerland, October 29, 1989.
Reprint requests to Department of Otolaryngology, Bnai Zion Medical Center, PO Box 4940, Haifa 31096, Israel.
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