This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Changes in Titers After Therapy for Nasopharyngeal Carcinoma

H. Bryan Neel, III, MD, PhD; William F. Taylor, PhD

Arch Otolaryngol Head Neck Surg. 1990;116(11):1287-1290.

Abstract
• Using long-term follow-up data from a prospective, collaborative study of 182 North American patients, we evaluated the significance of various serologic tests for antibody to Epstein-Barr virus in predicting outcome after treatment in patients with nasopharyngeal carcinoma. We restudied these patients by examining repeated measurements of each titer at various times after diagnosis and treatment. We looked for associations between trends of titers, measured as the slope of log(titer) against time, and titer level, measured as the mean of log(titer), with the outcome: alive and no evidence of disease; alive with recurrence; or dead of nasopharyngeal carcinoma. We found that posttreatment sequential measurements do not predict outcome.

(Arch Otolaryngol Head Neck Surg. 1990;116:1287-1290)

Author Affiliations
From the Department of Otorhinolaryngology (Dr Neel) and the Section of Biostatistics (Dr Taylor), Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Accepted for publication July 23, 1990.

Read before the American Society for Head and Neck Surgery, Palm Beach, Fla, April 30-May 1, 1990.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr Neel).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Single-Assay Combination of Epstein-Barr Virus (EBV) EBNA1- and Viral Capsid Antigen-p18-Derived Synthetic Peptides for Measuring Anti-EBV Immunoglobulin G (IgG) and IgA Antibody Levels in Sera from Nasopharyngeal Carcinoma Patients: Options for Field Screening
Fachiroh et al.
J. Clin. Microbiol. 2006;44:1459-1467.
ABSTRACT | FULL TEXT