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Lanny G. Close, MD; Steven D. Schaefer, MD; Bruce E. Mickey, MD; Scott C. Manning, MD

Arch Otolaryngol Head Neck Surg. 1989;115(9):1091-1095.

Abstract
• Involvement of the cavernous sinus by juvenile nasopharyngeal angiofibroma represents a therapeutic challenge. We present our experience over the past 5 years with the surgical management of six cases of juvenile nasopharyngeal angiofibroma involving this site. Three of six patients had involvement of the medial aspect of the cavernous sinus and tumor was removed using a midline extracranial approach. Of three remaining patients, two had invasion of the medial and inferior margin of the cavernous sinus and one represented a recurrent lesion. The tumor in these three cases was resected using a combined frontotemporal and lateral infratemporal fossa approach. An extracranial recurrence occurred in one patient, and the remaining five patients have had no evidence of recurrent disease 12 to 71 months following surgery. Morbidity has been limited to trismus, facial hypesthesia, and serous otitis media.

(Arch Otolaryngol Head Neck Surg. 1989;115:1091-1095)

Author Affiliations
From the Departments of Otorhinolaryngology (Drs Close, Manning, and Schaefer) and Neurosurgery (Dr Mickey), University of Texas Southwestern Medical Center, Dallas.

Footnotes
Accepted for publication March 30, 1989.

Presented at the International Symposium on Cranial Base Surgery, Pittsburgh, Pa, September 15, 1988.

Reprint requests to Department of Otorhinolaryngology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235-9035 (Dr Close).

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