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Ya-Yen Lee, MD; Isaiah W. Dimery, MD; Pamela Van Tassel, MD; Charles De Pena, MD; J. Bob Blacklock, MD; Helmuth Goepfert, MD

Arch Otolaryngol Head Neck Surg. 1989;115(4):503-511.

Abstract
• Twenty-four patients with advanced paranasal sinus tumors were treated with combined superselective intra-arterial and systemic chemotherapy, yielding an immediate satisfactory tumor response rate of 91%, significantly better than previously reported. Eight patients had craniofacial surgery circumvented because of complete or near complete response. Repetitive uncomplicated catheterization of the pterygoid segment of the internal maxillary artery using a coaxial system is the cornerstone of successful induction chemotherapy. Strenuous screening of medical status is mandatory for this aggressive introduction chemotherapy.

(Arch Otolaryngol Head Neck Surg 1989;115:503-511)

Author Affiliations
From the Division of Diagnostic Imaging, Department of Diagnostic Radiology (Drs Lee, Van Tassel, and De Pena); the Division of Internal Medicine, Section of Head and Neck Oncology (Dr Dimery); and the Department of Head and Neck Surgery (Drs Blacklock and Goepfert), The University of Texas M. D. Anderson Cancer Center, Houston.

Footnotes
Accepted for publication Oct 20, 1988.

Reprint requests to Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 (Dr Lee).

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