 |
|
Interobserver Variability in the Interpretation of Fine-Needle Aspiration Biopsy of Head and Neck Masses
B. Robert Peters, MD;
Vicki J. Schnadig, MD;
Francis B. Quinn, Jr, MD;
James A. Hokanson, PhD;
Paul Zaharopoulos, MD;
M. Melinda McCracken, MS;
Charles M. Stiernberg, MD;
Lee Des Jardins, CT (ASCP)
Arch Otolaryngol Head Neck Surg. 1989;115(12):1438-1442.
Abstract
| |
• Fine-needle aspiration biopsy is gaining acceptance as a clinically useful tool. We set out to evaluate the accuracy of fine-needle aspiration biopsy at our institution by measuring the interobserver variability in cytopathologic interpretation, and by measuring the agreement between cytopathologic and histologic diagnosis. In a prospective study, 253 aspirations were performed on head and neck masses by the otolaryngology service. Specimens were interpreted independently by two cytopathologists (V.J.S. and P.Z.), and interpretations were compared with the surgical histopathologic diagnosis when available. The interobserver variability between cytopathologists was 8% with a specificity of 96% and a sensitivity of 97%. We conclude that fine-needle aspiration biopsy is a safe and useful tool in the diagnosis of head and neck masses. In the diagnosis of epithelial cysts and squamous epithelial malignancies, fine-needle aspiration biopsy is as accurate as open biopsy.
(Arch Otolaryngol Head Neck Surg. 1989;115:1438-1442)
Author Affiliations
From the Departments of Otolaryngology (Drs Peters, Quinn, Hokanson, and Stiernberg and Ms McCracken) and Pathology (Drs Schnadig, Quinn, and Zaharopoulos and Ms Des Jardins), University of Texas Medical Branch, Galveston.
Footnotes
Accepted for publication April 25, 1989.
Reprint requests to University of Texas Medical Branch, Department of Otolaryngology, E-21, Galveston, TX 77550 (Dr Quinn).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Prospective Study on Neck Dissection after Primary Chemoradiation Therapy in Stage IV Pharyngeal Cancer
BREMKE et al.
Anticancer Res 2009;29:2645-2653.
ABSTRACT
| FULL TEXT
Interobserver Variability in the Interpretation of Brush Cytologic Studies From Head and Neck Lesions
Nichols et al.
Arch Otolaryngol Head Neck Surg 1991;117:1350-1355.
ABSTRACT
Ultrasound-Guided Fine-Needle Aspiration Biopsy of Neck Nodes
de Jong et al.
Arch Otolaryngol Head Neck Surg 1991;117:402-404.
ABSTRACT
Submandibular Gland Tumors: Adverse Histologic Factors and Therapeutic Implications
Weber et al.
Arch Otolaryngol Head Neck Surg 1990;116:1055-1060.
ABSTRACT
|
