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Human Leukocyte Antigen in Childhood Unilateral Deafness
Kazumasa Matsuki, MD;
Takehiko Harada, MD;
Takeo Juji, MD;
Jin Kanzaki, MD;
Keijiro Koga, MD;
Minoru Toriyama, MD
Arch Otolaryngol Head Neck Surg. 1989;115(1):46-47.
Abstract
Human leukocyte antigen frequencies were examined in 40 Japanese patients with severe unilateral sensorineural hearing loss found in childhood. Human leukocyte antigen-Bw54 was significantly increased in frequency. No statistically significant deviation in the Bw54 frequency was observed among several possible subgroups studied. Although this group of patients may have various causes, and underlying mechanism is still unclear, this preliminary study suggests that childhood unilateral deafness may be associated with a genetically determined factor(s).
(Arch Otolaryngol Head Neck Surg 1989;115:46-47)
Author Affiliations
From the Blood Transfusion Service, Tokyo University Hospital (Drs Matsuki and Juji); Department of Otolaryngology, University of Tokyo School of Medicine (Dr Harada); Department of Otolaryngology, Keio University School of Medicine (Dr Kanzaki); Division of Otolaryngology, National Children's Hospital (Dr Koga); Division of Otolaryngology, National Medical Center Hospital (Dr Toriyama), Tokyo.
Footnotes
Accepted for publication Sept 21, 1988.
Reprint requests to Department of Otolaryngology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan (Dr Harada).
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