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Matthew Lando, MD; Larry A. Hoover, MD; Gerald Finerman, MD

Arch Otolaryngol Head Neck Surg. 1988;114(8):891-894.

Abstract
• Paget's disease is a common skeletal disease characterized by abnormal bony resorption and deposition. Although the disease principally affects the axial skeleton, skull and temporal bone involvement occur. Affected individuals have significantly different rates of progression of hearing loss than normal persons. We describe two patients in whom this progressive hearing loss was halted and even reversed. These patients were treated with calcitonin and etidronate disodium and have been followed up for five and 3 years, respectively. Computed tomographic scans demonstrating extent of disease are included along with our treatment regimen and alkaline phosphatase response curves.

(Arch Otolaryngol Head Neck Surg 1988;114:891-894)

Author Affiliations
From the Divisions of Head and Neck Surgery (Drs Lando and Hoover) and Orthopedics (Dr Finerman), UCLA School of Medicine.

Footnotes
Accepted for publication March 28, 1988.

Reprint requests to the Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90024 (Dr Hoover).

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