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Efficacy of Defibrinogenation and Steroid Therapies on Sudden Deafness
Takeshi Kubo, MD;
Tohru Matsunaga, MD;
Hideyo Asai, MD;
Kazutomo Kawamoto, MD;
Jun Kusakari, MD;
Yasuya Nomura, MD;
Makoto Oda, MD;
Noriyuki Yanagita, MD;
Hideto Niwa, MD;
Takuya Uemura, MD;
Shizuo Komune, MD
Arch Otolaryngol Head Neck Surg. 1988;114(6):649-652.
Abstract
• Effects of defibrinogenation therapy and steroid therapy for sudden deafness were compared by paired double-blind testing. The average hearing recovery for five frequencies (250 to 4000 Hz) was more than 30 dB; overall improvement rate was 57.3% (47/82) for the patients assigned to defibrinogenation therapy and 38.7% (31/80) for the patients assigned to steroid therapy. Thus, the former treatment resulted in significantly better hearing recovery.
(Arch Otolaryngol Head Neck Surg 1988;114:649-652)
Author Affiliations
From the Osaka (Japan) University School of Medicine (Drs Kubo, Matsunaga, and Asai); Tohoku (Japan) University School of Medicine (Drs Kawamoto and Kusakari); Tokyo University School of Medicine (Drs Nomura and Oda); Nagoya (Japan) University School of Medicine (Drs Yanagita and Niwa); and Kyushu (Japan) University School of Medicine (Drs Uemura and Komune).
Footnotes
Accepted for publication Feb 1, 1988.
Reprint requests to Department of Otolaryngology, Osaka University School of Medicine, Fukushima-ku, Osaka 553, Japan (Dr Kubo).
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