This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Report of Seven Cases With Review of the Literature

Alfio Ferlito, MD; Giuseppe Caruso, MD; Gianfranco Recher, MD

Arch Otolaryngol Head Neck Surg. 1988;114(6):635-639.

Abstract
• Laryngeal metastases are uncommon, particularly if we consider only secondary involvement from the remote primary neoplasm, via lymphohematogenous dissemination. In the 21-year period from 1966 to 1986, only seven cases of secondary laryngeal cancers were observed at the Department of Otolaryngology of Padua (Italy) University. A review of the world literature resulted in the identification of 113 previously reported cases. Cutaneous melanoma is the neoplasm most frequently metastasizing to the larynx, but adenocarcinoma may also often occur, especially from renal origin. A correct differential diagnosis from primary laryngeal cancer is most important. Identification of tumor location beneath intact mucosa, use of particular biochemical and histochemical stains, and electron microscopy may assist in establishing the presence of a metastatic growth. The prognosis is almost generally unfavorable because laryngeal involvement often occurs with metastases to other organs.

(Arch Otolaryngol Head Neck Surg 1988;114:635-639)

Author Affiliations
From the Department of Otolaryngology, University of Padua (Italy) (Drs Ferlito and Caruso) and the Division of Otolaryngology, St Bortolo Hospital, Vicenza, Italy (Dr Recher).

Footnotes
Accepted for publication Jan 11, 1988.

Reprint requests to Department of Otolaryngology, Padua University, Nuovo Policlinico, via Giustiniani 2, 35100 Padua, Italy (Dr Ferlito).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?