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Richard S. Hodgson, MD; Robert E. Brummett, PhD; Ted A. Cook, MD

Arch Otolaryngol Head Neck Surg. 1987;113(9):950-952.

Abstract
• We studied the effects of pentoxifylline on experimental skin flap survival in the domestic pig. Random skin flaps were designed using a length-width ratio of 5:1. The pigs were then given pentoxifylline (25 mg/kg/d) or placebo for seven days. Fluorescein sodium was used to help determine surviving skin flap length seven days postoperatively. Results showed no significant difference in mean surviving skin flap length between the study and control groups. We question the value of pentoxifylline in increasing skin flap survival.

(Arch Otolaryngol Head Neck Surg 1987;113:950-952)

Author Affiliations
From the Department of Otolaryngology, Oregon Health Sciences University, Portland.

Footnotes
Accepted for publication April 20, 1987.

Reprint requests to Department of Otolaryngology, Oregon Health Sciences University, 3181 Sam Jackson Park Rd SW, Portland, OR 97201 (Dr Hodgson).

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