This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

MAJ James R. Wells, MC; COL William H. Gernon, MC

Arch Otolaryngol Head Neck Surg. 1987;113(6):644-646.

Abstract
• We investigated the effects of 2-cyano-butyl-acrylate (Histoacryl) on the ossicles of 11 of 12 adult guinea pigs. A small amount of the adhesive, placed precisely between the incus and its bony fossa in each middle ear, fixed the ossicles. Light microscopic investigation of the ears of animals killed at 3, 6, 9, and 12 months after surgery showed a bony union of the ossicle to its surrounding niche in 11 of 12 operated-on ears. Negligible inflammatory reaction was seen in areas of the middle ear not in contact with the adhesive. These observations suggest that 2-cyano-butyl-acrylate may be used to achieve a durable bony union in ossiculoplastic surgery with minimal side effects in the middle ear.

(Arch Otolaryngol Head Neck Surg 1987;113:644-646)

Author Affiliations
USA; USA

From the Otolaryngology—Head and Neck Surgery Service, Madigan Army Medical Center, Tacoma, Wash. Dr Wells is presently with the CENTA Medical Group, Columbia, SC.

Footnotes
Accepted for publication Dec 1, 1986.

The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.

Reprint requests to CENTA Medical Group, 1639 Brabham Ave, Columbia, SC 29204 (Dr Wells).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Legal Liability in Using Nonapproved Materials
RAYMOND
Arch Otolaryngol Head Neck Surg 1987;113:1238-1239.
ABSTRACT