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Endodermal Sinus Tumor (Yolk Sac Tumor) of the Ear
Robert J. Stanley, MD;
Bernd W. Scheithauer, MD;
Elizabeth I. Thompson, MD;
David B. Kispert, MD;
Louis H. Weiland, MD;
Bruce W. Pearson, MD
Arch Otolaryngol Head Neck Surg. 1987;113(2):200-203.
Abstract
• Endodermal sinus tumors (yolk sac tumors) are malignant germ cell tumors that usually arise in the gonads. We report what is, to our knowledge, the first known case of an endodermal sinus tumor of the ear. The tumor was present in a developmentally delayed child with an abnormal temporal bone and exhibited histopathologic and immunocytochemical features identical to those of endodermal sinus tumors of gonadal origin. The tumor resolved after chemotherapy, and the patient remained alive without evidence of disease at the time of this writing. The purpose of this report is to add a rare tumor to the differential diagnosis of neoplasms of the ear in children and to familiarize otorhinolaryngologists and head and neck surgeons with its pathologic features and clinical management.
(Arch Otolaryngol Head Neck Surg 1987;113:200-203)
Author Affiliations
From the Departments of Otorhinolaryngology (Drs Stanley and Pearson) and Diagnostic Radiology (Dr Kispert) and the Section of Surgical Pathology (Drs Scheithauer and Weiland), Mayo Clinic and Mayo Foundation, Rochester, Minn, and the Department of Hematology/Oncology, St Jude Children's Research Hospital, Memphis (Dr Thompson).
Footnotes
Accepted for publication March 21, 1986.
Presented in part at the 13th World Congress of Otorhinolaryngology, Miami Beach, Fla, May 31, 1985.
Reprint requests to Section of Surgical Pathology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr Scheithauer).
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