This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Birgitte Østberg, MD; Birgit Winther, MD; Niels Mygind, MD

Arch Otolaryngol Head Neck Surg. 1987;113(2):160-162.

Abstract
• A high dose of the cholinoceptor antagonist ipratropium bromide, in the form of a nasal spray, was tested on cold air– and hot soup–induced rhinorrhea in order to determine to what extent these types of rhinorrhea are reflex-mediated hypersecretions from nasal glands. Fourteen normal volunteers were examined in a placebo-controlled study. A single dose of ipratropium bromide (400 µg) caused a 73% reduction of cold air–induced rhinorrhea and a 66% reduction of hot soup– induced rhinorrhea. It is concluded that a major part of the nasal discharge induced by these stimuli is reflex-mediated, and consequently may be treated by a cholinoceptor antagonist, such as ipratropium.

(Arch Otolaryngol Head Neck Surg 1987;113:160-162)

Author Affiliations
From the Otopathological Laboratory, Department of Otorhinolaryngology, Rigshospitalet, Copenhagen.

Footnotes
Accepted for publication Aug 26, 1986.

Reprint requests to Otopathological Laboratory, Department of Otorhinolaryngology, Rigshospitalet, DK-2100 Copenhagen, Denmark (Dr Mygind).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?