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Fine-Needle Aspiration vs Frozen-Section Diagnosis

Michael B. Cohen, MD; Britt-Marie E. Ljung, MD; Roger Boles, MD

Arch Otolaryngol Head Neck Surg. 1986;112(8):867-869.

Abstract
• We examined the relative accuracy of fine-needle aspiration biopsy (FNAB) and frozen section (FS) in the diagnosis of salivary gland tumors; FNAB completely and accurately diagnosed 35 (88%) of 40 cases, including ten (100%) of ten nonneoplastic lesions, 20 (87%) of 23 benign, and five (71%) of seven malignant tumors. No complications were encountered with this procedure. These results compare favorably with previously published reports. Twénty-one of 40 tumors diagnosed by FNAB and FS at surgery. Sixteen (76%) of 21 of these were correctly diagnosed by FNAB, and 15 (71%) of 21 by FS. Cystic lesions gave the most diagnostic difficulties both on FNAB and FS. Worldwide, FNAB has been demonstrated to be a cost-effective, accurate, and safe procedure. Furthermore, the use of FNAB allows for better preoperative management and overall treatment planning.

(Arch Otolaryngol Head Neck Surg 1986;112:867-869)

Author Affiliations
From the Departments of Pathology (Drs Cohen and Ljung) and Otorhinolaryngology (Dr Boles), School of Medicine, University of California at San Francisco.

Footnotes
Accepted for publication Dec 4, 1985.

Reprint requests to Department of Pathology, HSW-501, School of Medicine, University of California, San Francisco, CA 94143 (Dr Ljung).

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