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Oncocytic and Oncocytoid Carcinoid Tumors (Well-Differentiated Neuroendocrine Carcinomas) of the Larynx
Robert J. Stanley, MD;
Lawrence W. DeSanto, MD;
Louis H. Weiland, MD
Arch Otolaryngol Head Neck Surg. 1986;112(5):529-535.
Abstract
• Carcinoid tumors of the larynx are exceedingly rare neoplasms. With the inclusion of the five neoplasms we report herein, the total number reported in the English-language literature is 16. These five neoplasms all showed light microscopic features of oncocytic (or oncocytoid) cells. Ultrastructurally, all lesions contained dense-core granules of the neurosecretory type. One case further met the ultrastructural criteria for true oncocytoma (that is, an oncocytic carcinoid). The lesion did not metastasize, and the patient was successfully treated surgically. In the other four cases, the lesions were considered to be oncocytoid carcinoids, since they failed to meet the ultrastructural requirements of a true oncocytoma. Each of these four lesions metastasized, although one patient did have a long, indolent course.
(Arch Otolaryngol Head Neck Surg 1986;112:529-535)
Author Affiliations
From the Department of Otorhinolaryngology (Drs Stanley and DeSanto) and Section of Surgical Pathology (Dr Weiland), Mayo Clinic and Mayo Foundation, Rochester, Minn.
Footnotes
Accepted for publication Sept 6, 1985.
Read before the joint meeting of the American Society for Head and Neck Surgery and the Society of Head and Neck Surgeons, Cerromar, Puerto Rico, May 6, 1985.
Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55905 (Dr DeSanto).
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