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Oropharynx Decontamination Preventing Candida Vegetation on Voice Prostheses
Hans F. Mahieu, MD;
Joris J. M. van Saene, PharmD;
Jan den Besten, MD;
Hendrik K. F. van Saene, MD, PhD
Arch Otolaryngol Head Neck Surg. 1986;112(10):1090-1092.
Abstract
• Candida vegetations found in silicone voice prostheses used in postlaryngectomy voice rehabilitation are associated with prothesis dysfunction. Selective oropharyngeal decontamination with amphotericin B lozenges resulted in sharp decrease of oropharyngeal Candida concentrations with a subsequent reduction of yeast colonization on voice protheses and in tracheoesophageal fistula in ten patients. A case report suggests that this selective oropharyngeal decontamination can prolong the device's lifetime.
(Arch Otolaryngol Head Neck Surg 1986;112:1090-1092)
Author Affiliations
From the Ear, Nose, and Throat Clinic, University Hospital (Drs Mahieu and den Besten), and the Faculty of Pharmacy, Division of Microbiology, State University (Drs J. van Saene and H. van Saene), Groningen, the Netherlands.
Footnotes
Accepted for publication March 5, 1986.
Reprint requests to Ear, Nose, and Throat Clinic, University Hospital, PO Box 30.001, 9700 RB Groningen, the Netherlands (Dr Mahieu).
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