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A Multi-Institutional Prospective Study

Bruce Leipzig, MD; James E. Zellmer, MD; Dean Klug; The Panendoscopy Study Group

Arch Otolaryngol. 1985;111(9):589-594.

Abstract
• In a prospective multi-institutional study of 384 patients undergoing endoscopy, an 8.9% incidence of second primary neoplasms was discovered simultaneously in the lung (3.3%), esophagus (1.8%), and other head and neck sites (3.6%). The endoscopy was the only source of detection of these tumors in 58% of cases. A trend indicates that flexible fiberoptic bronchoscopy was more effective than rigid bronchoscopy in discovering lung tumors (7.5% vs 2.3%). Nevertheless, the chest roentgenogram remains an important tool in the diagnosis of second primary lesions in the lung. Panendoscopy is safe, takes little time, and can add invaluable information concerning therapy in patients with head and neck cancers.

(Arch Otolaryngol 1985;111:589-594)

Author Affiliations
From the University of Arkansas for Medical Sciences, Little Rock.

Footnotes
Accepted for publication March 5, 1985.

Reprint requests to Central Arkansas Head and Neck Surgery Clinic, 2001 Fendley Dr, North Little Rock, AR 72114 (Dr Leipzig).

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