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Airway Obstruction in an Immunosuppressed Child
Charles M. Myer, III, MD;
James S. Reilly, MD
Arch Otolaryngol. 1985;111(6):409-411.
Abstract
• Recipients of organ transplants who require continuous immunosuppression appear to have an increased incidence of lymphoproliferative disorders. A case of severe upper airway obstruction resulted from adenotonsillar hypertrophy in a 2-year-old girl following liver transplantation. Tonsillectomy and adenoidectomy dramatically reversed the airway problem and confirmed a transplant-associated lymphoproliferative disorder. A generalized lymphadenopathy also regressed with reduction of cyclosporine immunosuppression. We urge vigilance in monitoring transplant recipients, particularly children, for problems of upper airway obstruction and advocate prompt biopsy of persistently enlarged lymphoid tissue in all immunosuppressed individuals who fail to respond to conventional medical therapy.
(Arch Otolaryngol 1985;111:409-411)
Author Affiliations
From the Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, and the Department of Otolaryngology, University of Pittsburgh School of Medicine.
Footnotes
Accepted for publication Feb 12, 1985.
Reprint requests to Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, 125 DeSoto St, Pittsburgh, PA 15213 (Dr Myer).
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