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Prevention of Hearing Impairment From Infection and Ototoxic Drugs
Francis I. Catlin, MD, ScD
Arch Otolaryngol. 1985;111(6):377-384.
Abstract
Infectious diseases are a primary cause of hearing impairment and produce about 25% of profound losses. Of these, one fifth are congenital. The major infections include rubella, cytomegalovirus, measles, pertussis, meningitis, and acute otitis media. Hearing loss from ototoxicity is also observed with a number of drugs, notably the aminoglycosides, loop diuretics, and cisplatin. Preventive measures are defined according to primary, secondary, and tertiary principles. Three principles of prevention are considered: direct action, defined objectives, and the variability of effective prevention according to cause.
(Arch Otolaryngol 1985;111:377-384)
Author Affiliations
From Baylor College of Medicine, Houston.
Footnotes
Accepted for publication Nov 16, 1984.
Read before the 17th International Congress of Audiology, Santa Barbara, Calif, Aug 27, 1984.
Reprint requests to Department of Otolaryngology, Texas Children's Hospital, Box 20269, Houston, TX 77225 (Dr Catlin).
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