This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Janice P. Handlers, DDS; Jeffrey Waterman, DDS; Albert M. Abrams, DDS, MS; Raymond J. Melrose, DDS

Arch Otolaryngol. 1985;111(4):267-270.

Abstract
• A review of the dental literature yielded ten cases of Wegener's granulomatosis manifesting in the oral cavity, but only one was found in the medical literature. The most common oral lesion is hyperplastic gingiva, which is red to purple, with many petechiae. Tooth mobility, loss of teeth, and failure of wounds to heal are also common manifestations. The disease may remain localized in the oral cavity for unusually long periods of time before multiorgan involvement occurs. Histologically, oral biopsy tissue does not exhibit the characteristic features of vasculitis and granulomas. There are, however, diagnostic histologic features that are consistently present, including pseudoepitheliomatous hyperplasia, epithelioid histiocytes, giant cells, and eosinophils. Failure to recognize these diagnostic clinical and histologic features resulted in a 24-month delay in the diagnosis and treatment of our patient.

(Arch Otolaryngol 1985;111:267-270)

Author Affiliations
From the Department of Pathology, University of Southern California School of Dentistry, Los Angeles (Drs Handlers, Abrams, and Melrose). Dr Waterman is in private practice in Los Angeles.

Footnotes
Accepted for publication Sept 5, 1984.

Reprint requests to Department of Pathology, University of Southern California School of Dentistry, University Park, MC 0641, Los Angeles, CA 90089-0641 (Dr Handlers).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Oral manifestations of Wegener's granulomatosis: A report of three cases and a literature review
Stewart et al.
Journal of the American Dental Association 2007;138:338-348.
ABSTRACT | FULL TEXT  

Wegener's Granulomatosis: Dermatological Manifestations in 75 Cases With Clinicopathologic Correlation
Frances et al.
Arch Dermatol 1994;130:861-867.
ABSTRACT