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Extraordinary Growth of Giant Cell Reparative Granuloma During Pregnancy
Robert E. Fechner, MD;
G. Slaughter Fitz-Hugh, MD;
Thomas L. Pope, Jr, MD
Arch Otolaryngol. 1984;110(2):116-119.
Abstract
• A 25-year-old woman had a giant cell reparative granuloma (GCRG) in the nasal fossa during the fifth month of pregnancy. This was treated with a partial excision, but the lesion recurred three months later. By this time, there was extension into the anterior fossa. Because of rapidly decreasing visual acuity, headache, and facial pain, a combined craniofacial approach was undertaken. The lesion encroached on the optic chiasm and a piecemeal, but incomplete, removal of the lesion was performed. The patient spontaneously gave birth to a normal child while in the recovery room. She received no additional therapy and her symptoms disappeared. She remains well 11 years later. The course of disease in this patient is compared with eight other patients from the literature who had GCRG during pregnancy.
(Arch Otolaryngol 1984;110:116-119)
Author Affiliations
From the Departments of Pathology (Dr Fechner), Otolaryngology—Head and Neck Surgery (Dr Fitz-Hugh), and Radiology (Dr Pope), University of Virginia Medical Center, Charlottesville.
Footnotes
Accepted for publication Feb 3, 1983.
Read in part before the meeting of the International Skeletal Society, San Francisco, Aug 31, 1982.
Reprint requests to Department of Pathology, Box 214, University of Virginia Medical Center, Charlottesville, VA 22908 (Dr Fechner).
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