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Radionuclide Thyroid Angiography and Surgical CorrelationA Five-Year Study
Roderick D. Moe, MD;
Sam F. Frankel, MD;
Anna K. Chacko, MD;
Donald W. S. Yim, MD;
Merritt W. Clark, III
Arch Otolaryngol. 1984;110(11):717-720.
Abstract
• Only 15% to 25% of cold nodules on conventional static thyroid scans are malignant. Radionuclide angiography of the thyroid and conventional static scans using sodium pertechnetate Tc 99m were performed on 114 patients who underwent thyroid surgery within a five-year period. The combined use of radionuclide angiography and conventional static scans increased the specificity for the diagnosis of thyroid carcinoma from 42% to 79% over static scans alone. The incidence of carcinoma in solitary cold nodules in our population was increased from 26% on static scans to 60% if the lesion was hypervascular on radionuclide angiography. Eighty-seven percent of hypervascular solitary cold nodules were neoplasms (carcinomas and adenomas). Hypervascularity as demonstrated by radionuclide angiography is predictive of thyroid neoplasia. The finding of a hypervascular, solitary cold nodule makes a recommendation for surgery predictive and reasonable.
(Arch Otolaryngol 1984;110:717-720)
Author Affiliations
From the Otorhinolaryngology-Head and Neck Surgery Service (Drs Moe, Frankel, and Yim) and the Nuclear Medicine Service (Dr Chacko and Mr Clark), Tripler Army Medical Center, Honolulu.
Footnotes
Accepted for publication Aug 3, 1984.
Read before the American Society for Head and Neck Surgery, Palm Beach, Fla, May 10, 1984.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.
Reprint requests to the Otorhinolaryngology-Head and Neck Surgery Service, Department of Surgery, Tripler Army Medical Center, Tripler AMC, Hawaii 96859 (Dr Frankel).
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