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A Study of Patients With Allergic Rhinitis

Samy Elwany, MD, PhD; Mokhtar Toppozada, MD, PhD

Arch Otolaryngol. 1983;109(12):815-817.

Abstract
• We studied the effects of topical dinoprostone on the nasal blood vessels of patients with allergic rhinitis. The outstanding changes noted were constriction of the arterioles and capillaries (to a lesser extent) and tight closure of the interendothelial junctions. These changes caused a diminution of nasal blood flow and edema fluid formation, a reduction in the size of the turbinates, and consequently, an increase in nasal patency. However, dinoprostone had no effect on the nasal venules.

(Arch Otolaryngol 1983;109:815-817)

Author Affiliations
From the Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City (Dr Elwany); and the Department of Obstetrics and Gynecology, Alexandria (Egypt) Faculty of Medicine (Dr Toppozada). Dr Elwany is a fellow of University of Iowa, Iowa City, and a lecturer at the Alexandria Faculty of Medicine.

Footnotes
Accepted for publication April 18, 1983.

Reprint requests to 503 El-Horreya St, Boulkeley, Alexandria, Egypt (Dr Elwany).

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