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Philip S. Feldman, MD; Michael J. Kaplan, MD; Michael E. Johns, MD; Robert W. Cantrell, MD

Arch Otolaryngol. 1983;109(11):735-742.

Abstract
• Cytological examination of fine-needle aspiration (FNA) specimens from patients with known or suspected squamous cell carcinoma of the head and neck at the University of Virginia, Charlottesville, between 1979 and 1982 was reviewed. Of 229 aspirates, 187 were of cervical or submandibular sites and 42 were of oral cavity sites. The accuracy of cytological diagnoses was determined by histological comparison and clinical follow-up. There were no false-positive aspirates (specificity, 100%) and one false-negative aspirate (sensitivity, 99%). Twenty-one (9%) contained insufficient cellular material for adequate cytological diagnosis. Seventy-eight percent of histologically confirmed aspirations were malignant. Proper use requires close communication between an experienced cytologist and a head and neck surgeon knowledgeable in the indications and limitations of the technique. This study demonstrates that FNA is a highly accurate, safe, predictive, and valuable technique in the management of squamous cell carcinoma of the head and neck.

(Arch Otolaryngol 1983;109:735-742)

Author Affiliations
From the Departments of Otolaryngology–Head and Neck Surgery (Drs Kaplan, Johns, and Cantrell) and Pathology (Dr Feldman), University of Virginia Medical Center, Charlottesville. Dr Kaplan is a regular clinical fellow of the American Cancer Society.

Footnotes
Accepted for publication June 3, 1983.

Read before the American Society for Head and Neck Surgery, Palm Springs, Calif, March 13, 1983.

Reprint requests to Department of Pathology, University of Virginia Medical Center, Box 214, Charlottesville, VA 22908 (Dr Feldman).

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