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Prospective Correlative Trial

Douglas E. Mattox, MD; Daniel D. Von Hoff, MD; Lenore L. Harris, RN, MSN

Arch Otolaryngol. 1983;109(11):724-726.

Abstract
• The feasibility and usefulness of chemosensitivity testing with the soft agar cloning assay was tested in 20 patients with advanced head and neck cancer. Pretreatment biopsy specimens could be obtained on only 13 of 20 patients, and chemosensitivity testing could be performed in only two patients. As currently used, the soft agar cloning assay does not contribute to the management of patients with advanced head and neck cancer.

(Arch Otolaryngol 1983;109:724-726)

Author Affiliations
From the Divisions of Otorhinolaryngology (Dr Mattox and Ms Harris) and Medical Oncology (Dr Von Hoff), The University of Texas Health Science Center at San Antonio and the Audie L. Murphy Veterans Hospital, San Antonio.

Footnotes
Accepted for publication May 12, 1983.

Read before the American Society for Head and Neck Surgery, Palm Springs, Calif, March 11, 1983.

Reprint requests to Division of Otorhinolaryngology, 7703 Floyd Curl Dr, San Antonio, TX 78284 (Dr Mattox).

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