This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Variations During Anoxia, Hyperoxia, and Hypercapnia

Jiri Prazma, MD, PhD

Arch Otolaryngol. 1982;108(9):539-543.

Abstract
• Cochlear microcirculation was studied with oxygen-sensitive microelectrodes simultaneously in all three scalas during anoxia, hyperoxia, and hypercapnia. The anoxia caused a sharp decline of Po₂ in the scala media (SM), scala vestibuli (SV), and scala tympani (ST). Hyperoxia and hypercapnia resulted in an elevation of Po₂ in all three scaias. During anoxia, the SM showed the earliest and largest decline in Po₂, with the shortest recovery and reoxygenation time. When Po₂ slopes (during anoxia) were compared, the SM to ST and the SM to SV were substantially different and remained different even when the partial pressures of oxygen quantified as oxygen in nanomoles. Our experiments also showed that changes in Po2 within the SM closely correlate with changes of endocochlear potential and BP.

(Arch Otolaryngol 1982;108:539-543)

Author Affiliations
From the Department of Surgery, Division of Otolaryngology, University of North Carolina, Chapel Hill.

Footnotes
Accepted for publication April 30, 1982.

Reprint requests to Department of Surgery, Division of Otolaryngology, 610 Burnett-Womack Bldg, 229H, University of North Carolina, Chapel Hill, NC 27514 (Dr Prazma).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Biophysical basis for inner ear decompression sickness
Doolette and Mitchell
J. Appl. Physiol. 2003;94:2145-2150.
ABSTRACT | FULL TEXT  

Innervation of the Endolymphatic Sac
Brechtelsbauer et al.
Arch Otolaryngol Head Neck Surg 1992;118:260-264.
ABSTRACT