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Musan Huangfu, MD; Shizuo Komune, MD; James B. Snow, Jr, MD

Arch Otolaryngol. 1982;108(9):535-538.

Abstract
• The dynamics of perilymph flow in the cochlea was studied in guinea pigs. After placement of sodium chloride crystals on the round window membrane, the potassium ion concentration in the scala vestibuli in the basal turn does not change. The potassium ion concentration in the scala tympani in the basal turn increases rapidly, while the potassium ion concentration in the scala tympani in the third turn increases slowly and to a lesser extent. The cochlear microphonic potential decreases in the basal turn and to a lesser extent in the third turn. After placement of sodium chloride on the fenestra in the scala tympani of the third turn, the chochlear microphonic potential in the basal turn does not change. These data lend support to the theory of longitudinal flow of perilymph in the scala tympani.

(Arch Otolaryngol 1982;108:535-538)

Author Affiliations
From the Department of Otorhinolaryngology and Human Communication, University of Pennsylvania School of Medicine, Philadelphia.

Footnotes
Accepted for publication March 30, 1982.

Presented at the Midwinter Research Meeting of the Association of Research in Otolaryngology, St Petersburg Beach, Fla, Jan 21, 1982.

Reprint requests to the Department of Otorhinolaryngology and Human Communication, University of Pennsylvania School of Medicine, 3400 Spruce St, Philadelphia, PA 19104 (Dr Snow).

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