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The Ototoxicity of Topically Applied Povidone-Iodine Preparations
Tetsuo Morizono, MD;
Michael A. Sikora
Arch Otolaryngol. 1982;108(4):210-213.
Abstract
• The ototoxicity of povidone-iodine solution and scrub, when topically applied to the round window of the chinchilla, was studied by means of compound action potentials. Povidone-iodine scrub has a greater ototoxic potential than povidone-iodine solution. One day after topical application of dilutions of 1% povidone-iodine solution, a 1:4 dilution showed a substantial ototoxic effect, while a 1:10 dilution did not.
(Arch Otolaryngol 1982;108:210-213)
Author Affiliations
From the Department of Otolaryngology, University of Minnesota Medical School, Minneapolis.
Footnotes
Accepted for publication Oct 28, 1981.
Read before the Fourth Midwinter Research Meeting of the Association for Research in Otolaryngology, St Petersburg Beach, Fla, Jan 21, 1981.
Reprint requests to Department of Otolaryngology, University of Minnesota Medical School, 2630 University Ave SE, Minneapolis, MN 55414 (Dr Morizono).
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