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The Superiority of Combined Therapy (Surgery and Postoperative Irradiation) in Parotid Cancer
Gui-yi Tu, MD;
Yu-hua Hu, MD;
Pei-jue Jiang;
De-xing Qin
Arch Otolaryngol. 1982;108(11):710-713.
Abstract
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A retrospective evaluation was done on 120 patients treated for parotid cancer. The aim of the study was to establish the role of postoperative radiation therapy. Fifty-nine patients were treated by surgery alone and an equal number of patients received surgery plus postoperative radiation therapy. Two patients were treated by preoperative irrradiation. The overall 5-, 10-, and 15-year survival rates were 81%, 62%, and 65%, respectively. Postoperative radiation therapy proved to increase local control over surgery alone whenever (1) there was locally advanced disease, (2) the tumor belonged to a so-called poorly differentiated variety, (3) the treatment was given for a recurrent lesion, and/or (4) there was tumor involvement of the facial nerve. It did not appear that postoperative radiation therapy increased the survival for patients with low-grade malignant tumors. Radiation therapy should be given as early as possible after surgery and the optimum dose ranges from 3,000 to 5,000 rad given in three to five weeks, respectively.
(Arch Otolaryngol 1982;108:710-713)
Author Affiliations
From the Head and Neck Division, Department of Surgery (Drs Tu and Jiang) and the Department of Radiation Oncology (Drs Hu and Qin), Cancer Hospital, Chinese Academy of Medical Sciences, Peking.
Footnotes
Accepted for publication May 28, 1982.
Reprint requests to Department of Surgery, Cancer Institute, Chinese Academy of Medical Sciences, No. 2, Ya Bao Road, Peking, People's Republic of China (Dr Tu).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Prognostic Variables in Parotid Gland Cancer
Frankenthaler et al.
Arch Otolaryngol Head Neck Surg 1991;117:1251-1256.
ABSTRACT
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