 |
|
Energy and Tissue Metabolism in Patients With Cancer During Nutritional Support
Staffan Edström, MD, PhD;
Klas Benneg rd, MD;
Elisabeth Edén, MD;
Kent Lundholm, MD, PhD
Arch Otolaryngol. 1982;108(11):697-699.
Abstract
• The present study evaluates the energy and skeletal muscle metabolism in malnourished patients, with and without cancer, in response to nutrition. The energy balance was positive in all patients receiving nutritional support. This led to an increase in body weight and body potassium levels. Glucose turnover increased in all patients. In patients with cancer, elevated glucose turnover reflected increased utilization of glucose preferentially for synthetic pathways rather than for oxidation. Protein synthesis and RNA content in skeletal muscles increased during nutrition. Nutritional support improved energy balance and protein synthesis capacity in skeletal muscles in patients with cancer to the same extent as in malnourished patients without cancer. Malignant cachexia seems to be a consequence of a relative lack of energy and not of impaired energy utilization in host tissues, at least early in the disease.
(Arch Otolaryngol 1982;108:697-699)
Author Affiliations
From the Department of Otolaryngology (Dr Edström) and the Surgical Metabolic Research Laboratory (Drs Edström, Bennegrd, Edén, and Lundholm), Sahlgren's Hospital, University of Gothenburg, Sweden.
Footnotes
Accepted for publication June 3, 1982.
Read in part before the American Society for Head and Neck Surgery, Palm Beach, Fla, May 6, 1982.
Reprint requests to Department of Otolaryngology, Sahlgren's Hospital, S-413 45 Gothenburg, Sweden (Dr Edström).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Early Postoperative Enteral Nutrition Improves Peripheral Protein Kinetics in Upper Gastrointestinal Cancer Patients Undergoing Complete Resection: A Randomized Trial
Harrison et al.
JPEN J Parenter Enteral Nutr 1997;21:202-207.
ABSTRACT
|
