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Michael Hawke, MD, FRCS(C); Malcolm Keene, FRCS

Arch Otolaryngol. 1981;107(9):581-583.

Abstract
• The pathogenesis of granulation tissue that arises periodically around artificial Eustachian tubes was elucidated by histologic examination of 15 cases of tube granuloma. All cases showed the presence of a keratin foreign-body granuloma. The implanted squames incited a foreign-body type of granulomatous reaction and produced a friable vascular exuberant mass that surrounded the artificial Eustachian tube. Histologically, the tube granuloma was characterized by the presence of irregular ovoid slit-like spaces that contained keratin squames, and it was surrounded by foreign-body giant cells.

(Arch Otolaryngol 1981;107:581-583)

Author Affiliations
From the Temporal Bone Histopathology Laboratory, and the Departments of Otolaryngology and Pathology, University of Toronto.

Footnotes
Accepted for publication Feb 16, 1981.

Reprint requests to Temporal Bone Histopathology Laboratory, The Banting Institute, 100 College St, Room 81, Toronto M5G 1L5, Ontario, Canada (Dr Hawke).

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