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Case Report and Literature Review

Prema V. Iyer, MB, BS, FRCPA; Pal V. Rajagopalan, MB, BS, DLO, MS

Arch Otolaryngol. 1981;107(9):573-575.

Abstract
• Cartilaginous metaplasia in the larynx is distinguished from true cartilaginous neoplasms by the occurrence of fibroblast-like cells at the periphery of islands of cartilage and a progressive transition of these cells to chondrocytes toward the center. Also present in the transitional zone was diffuse intercellular stromal acid mucopolysaccharide and dense aggregates of elastin fibers. The importance of distinguishing these metaplastic lesions from true neoplasms is emphasized.

(Arch Otolaryngol 1981;107:573-575)

Author Affiliations
From the Division of Tissue Pathology, Institute of Medical and Veterinary Science (Dr Iyer); and the Department of Otorhinolaryngology, Royal Adelaide Hospital (Dr Rajagopalan), Adelaide, South Australia.

Footnotes
Accepted for publication April 8, 1981.

Reprint requests to Division of Tissue Pathology, Institute of Medical and Veterinary Science, Frome Road, Adelaide 5000, South Australia (Dr Iyer).

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