This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Tauno Palva, MD; Erkki Tolvanen, MD; Yrjö T. Konttinen, MD; Sakari Reitamo, MD

Arch Otolaryngol. 1981;107(9):528-531.

Abstract
• Middle ear mucosal biopsy specimens were taken from 12 patients with chronic otitis media. The specimens from 11 cases contained enough inflammatory cells for a detailed study of the inflammatory cell subtypes in the lamina propria. T lymphocytes, mononuclear phagocytes, and plasma cells were the most frequent cell types except in two patients, in whom most of the inflammatory lymphocytes were B lymphocytes. The relative scarcity of B lymphocytes could be caused by activation and transformation to plasma cells. The close contact between different immunocompetent cells suggests T- and B-cell interactions. However, pseudolymphoid transformation with primary and secondary lymphatic follicles was observed in only one patient. The relative scarcity of granulocytes in the submucosal infiltrate could be caused by the movement of these cells through the epithelium into the discharge.

(Arch Otolaryngol 1981;107:528-531)

Author Affiliations
From the Department of Otorhinolaryngology (Dr Palva) and the Fourth Department of Medicine (Drs Tolvanen, Konttinen, and Reitamo), University of Helsinki, Finland.

Footnotes
Accepted for publication Feb 16, 1981.

Reprint requests to the Department of Otorhinolaryngology, Helsinki University Central Hospital, Haartmaninkatu 4, SF 00290 Helsinki 29, Finland (Dr Palva).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?