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Edward L. Treyve, MD; Larry G. Duckert, MD, PhD

Arch Otolaryngol. 1981;107(6):382-384.

Abstract
• A case of phenytoin sodium-induced lymphadenopathy appeared as a nasopharyngeal malignant neoplasm with regional metastases. Cervical lymphadenopathy is a lesser-known drug reaction that is produced by anticonvulsant therapy; under some circumstances, this condition may be confused with head and neck malignant neoplasms. To date, phenytoin-induced nasopharyngeal lymphadenopathy has not previously been reported in the literature. A review of the medical literature provides some interesting facts about the syndrome. A familiarity with this potential complication of anticonvulsant therapy may expedite early diagnosis and appropriate patient treatment.

(Arch Otolaryngol 1981;107:382-384)

Author Affiliations
From the Department of Otolaryngology, University of Washington School of Medicine, Seattle.

Footnotes
Accepted for publication Oct 15, 1980.

Reprint requests to Department of Otolaryngology, RL-30, University of Washington School of Medicine, Seattle, WA 98195 (Dr Duckert).

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