Chemotherapy before radiotherapy and/or surgery for locally advanced squamous cell carcinomas of the head and neck
M. W. Oster
Locally advanced (stage III and IV) squamous cell carcinomas of the head
and neck are not well controlled with surgery and/or radiotherapy. Trials
of chemotherapy before therapy is given for local disease are currently
being conducted in an attempt to improve survival and cure rates. Initial
studies are preliminary but suggest (1) possible benefit and (2) no
excessive toxic effects after surgery and/or radiotherapy. Head and neck
surgeons should be aware of the status of these studies.