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A Comparative Study

Rao V. P. Mantravadi, MD; Emanuel M. Skolnik, MD; Edward L. Applebaum, MD

Arch Otolaryngol. 1981;107(11):690-693.

Abstract
• The complications of planned postoperative irradiation in 60 consecutive patients treated between 1975 and 1979 are compared with those seen in 92 patients treated with preoperative irradiation between 1968 and 1974. The overall rate of complications requiring additional hospitalization was 15% (nine patients) in the postoperative radiotherapy group as compared with 54% (50 patients) in the preoperative radiotherapy group. A statistically significant increase in acute complications was noted in the latter group (46 vs three, 50% vs 5%). Delayed complications occurred with similar frequency in both groups. The three-year survival was comparable between similar patients of each group treated with either of the two modalities. We favor postoperative irradiation because of decreased acute complications and comparable survival. Modifications of the treatment technique are suggested to minimize the overall rate of complications.

(Arch Otolaryngol 1981;107:690-693)

Author Affiliations
From the Departments of Radiology (Dr Mantravadi) and Otolaryngology (Drs Skolnik and Applebaum), University of Illinois Hospital and Eye and Ear Infirmary, Chicago.

Footnotes
Accepted for publication May 7, 1981.

Read before the combined meeting of the Society of Head and Neck Surgeons and the American Society for Head and Neck Surgery, Phoenix, Ariz, March 10, 1981.

Reprint requests to Department of Radiology, University of Illinois Hospital, PO Box 6998, Chicago, IL 60680 (Dr Mantravadi).

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