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A. M. Nisar Syed, MD, FRCS; Ajmel Puthawala, MD; Peter Fleming, MD; Richard T. Barton, MD; Frederick W. George, III, MD

Arch Otolaryngol. 1980;106(9):541-546.

Abstract
• Seventy-nine patients with head and neck malignancies were treated using afterloading interstitial iridium 192 techniques at Los Angeles County-University of Southern California Medical Center and Southern California Cancer Center from Feb 1, 1974, to Nov 30, 1975. Twelve of the 13 T₁ and T₂ lesions and 17 of 25 T₃ and T₄ lesions remain locally controlled to a minimum follow-up period of 24 months. Surgical salvage in case of treatment failure is possible with low morbidity because of relatively low external irradiation to the total volume. Twenty of 41 patients who were reirradiated for persistent or recurrent cancers still have local control to a minimum follow-up period of 24 months. We discuss sites of involvement, implantation techniques, reactions, and complications.

(Arch Otolaryngol 106:541-546, 1980)

Author Affiliations
From the Department of Radiology, University of Southern California, Los Angeles (Dr Syed); the Department of Radiology, Los Angeles County-University of Southern California Medical Center (Drs Syed and George); the Southern California Cancer Center/California Hospital Medical Center (Drs Puthawala and Fleming); and the UCLA Cancer Center (Dr Barton), Los Angeles.

Footnotes
Accepted for publication July 5, 1979.

Reprint requests to 637 S Lucas Ave, Los Angeles, CA 90017 (Dr Syed).

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