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Aryeh Gorenstein, DDS, MD; Eugene B. Kern, MD; George W. Facer, MD; Edward R. Laws, Jr, MD

Arch Otolaryngol. 1980;106(9):536-540.

Abstract
• Nasal glioma is a developmental abnormality of neurogenic origin with no malignant potential. An intranasal mass requires careful rhinologic and occasionally ophthalmologic, neurologic, and roentgenologic examinations. With a bony defect, pneumoencephalography, angiography, or computerized tomography may be helpful. In such cases, a neurosurgeon should be available at the time of biopsy. Biopsy is necessary for establishing a histopathologic diagnosis. Aspiration of the tumor with a needle or incisional biopsy may yield inconclusive findings and may be associated with CSF rhinorrhea and meningitis, especially if there is an intracranial connection. With adequate initial removal, excisional biopsy usually offers complete cure. A frontal craniotomy approach is preferred for those patients who have nasal glioma with an intracranial connection, CSF rhinorrhea, or recurrent episodes of meningitis. With no evidence of an intracranial connection, a conservative extracranial approach is recommended.

(Arch Otolaryngol 106:536-540, 1980)

Author Affiliations
From the Departments of Otorhinolaryngology (Drs Gorenstein, Kern, and Facer) and Neurologic Surgery (Dr Laws), Mayo Clinic and Mayo Foundation, Rochester, Minn.

Footnotes
Accepted for publication Aug 14, 1979.

Read before the 24th Annual Scientific Meeting of the American Rhinologic Society, Los Angeles, Sept 8, 1978.

Reprint requests to Mayo Clinic, 200 First St SW, Rochester, MN 55901 (Dr Kern).

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