This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Side Effects in 2,347 Administrations

James L. Sheehy, MD; Jerald V. Robinson, MD; James E. Bush, MD

Arch Otolaryngol. 1980;106(3):159-160.

Abstract
• Intravenous (IV) histamine has been used extensively at the Otologic Medical Group, Inc, Los Angeles, for 30 years in the treatment of various conditions in which vasospasm was thought to play a part in the cause. We report the findings on 2,347 IV histamine administrations to 622 patients during a 33-month period. Dizziness was the indication for treatment in half of the patients. Sensorineural hearing impairment was the diagnosis in an additional 44%, and the majority of these had had a sudden impairment. Side effects were uncommon, never serious, and bore no relationship to the results of the histamine skin test or the patient's general medical problem. The IV histamine treatment resulted in improvement in symptoms in 36%, and almost half of those improvements were immediate.

(Arch Otolaryngol 106:159-160, 1980)

Author Affiliations
From the Otologic Medical Group, Inc, and the Ear Research Institute, Los Angeles.

Footnotes
Accepted for publication Jan 8, 1979.

Reprint requests to Otologic Medical Group, Inc, 2122 W Third St, Los Angeles, CA 90057 (Dr Sheehy).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?