This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Jukka Ylikoski, MD; Yrjö Collan, MD; Tauno Palva, MD

Arch Otolaryngol. 1979;105(8):486-491.

Abstract
• Utricle and horizontal semicircular canal ampulla removed during labyrinthectomy from 11 patients with advanced Meniere's disease were studied under light and electron microscope. In light microscopy the epithelium of both sensory areas appeared fairly normal. Many sensory cells revealed fluid-filled crescents at the nucleus and many cells were extensively vacuolated. Ultrastructurally, a part of the observations were apparently artifacts due to specimen handling; some were normal, age-related findings. Some changes were considered secondary to dilation of the endolymphatic space. True signs of degeneration, seldom seen in these specimens were intraepithelial cysts, necrotic cells, and dark homogeneous masses in the sensory epithelium and dilated nerve fibers in the subepithelial tissue. No general degeneration of the utricular macula or ampullar crista seems to occur in Meniere's disease.

(Arch Otolaryngol 105:486-491, 1979)

Author Affiliations
From the Department of Otolaryngology, University of Helsinki.

Footnotes
Accepted for publication Sept 21, 1978.

Reprint requests to Department of Otolaryngology, University of Helsinki, Haartmaninkatu 4, SF 00290, Helsinki 29, Finland (Dr Palva).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Vestibular Findings in Patients With Acoustic Neurinoma
Ylikoski et al.
Arch Otolaryngol Head Neck Surg 1980;106:723-726.
ABSTRACT  

The Cochlear Nerve in Meniere's Disease
Ylikoski et al.
Arch Otolaryngol Head Neck Surg 1980;106:396-400.
ABSTRACT