 |
|
Effects of Pentobarbital and Ketamine on Brain Stem Auditory PotentialsLatency and Amplitude Intensity Functions After Intraperitoneal Administration
Richard P. Bobbin, PhD;
James G. May, PhD;
Randall L. Lemoine, MS
Arch Otolaryngol. 1979;105(8):467-470.
Abstract
¶ Latency and amplitude intensity functions of two short latency (<5 ms) components (I and IV) of the brain stem auditory potentials were recorded from scalp electrodes in 18 paralyzed, hooded rats breathing with the assistance of artificial respirators. Averaged responses were obtained in three groups of rats before and 30 minutes after intraperitoneal injections of saline, ketamine hydrochloride (Ketalar), and pentobarbital sodium. Although both ketamine and pentobarbital significantly decreased heart rate and altered the gross EEG, they did not significantly change the latency or amplitude intensity functions of the two evoked-potential components.
(Arch Otolaryngol 105:467-470, 1979)
Author Affiliations
From the Kresge Hearing Laboratory of the South, Department of Otorhinolaryngology, Louisiana State University Medical Center, New Orleans (Drs Bobbin and May and Mr Lemoine), and the Department of Psychology, University of New Orleans (Dr May and Mr Lemoine).
Footnotes
Accepted for publication Sept 21, 1979.
Read as a preliminary report at the 89th meeting of the Acoustical Society of America, Austin, Tex, April 11, 1975.
Reprint requests to Louisiana State Medical Center, Kresge Hearing Research Laboratory of the South, 1100 Florida Ave, Bldg 164, New Orleans, LA 70119 (Dr Bobbin).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Effect of Ketamine on the Stapedius Reflex in the Squirrel Monkey
Thompson et al.
Arch Otolaryngol Head Neck Surg 1984;110:22-24.
ABSTRACT
Auditory Brainstem Responses During Systemic Infusion of Lidocaine
Javel et al.
Arch Otolaryngol Head Neck Surg 1982;108:71-76.
ABSTRACT
|
