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Is Surgical Resection Necessary?

Helmuth Goepfert, MD; Ayten Cangir, MD; Robert Lindberg, MD; Alberto Ayala, MD

Arch Otolaryngol. 1979;105(6):310-313.

Abstract
• Three patients had embryonal rhabdomyosarcoma of the temporal bone. Their clinical appearances demonstrated the following characteristics: (1) symptoms of an acute process in the middle ear cleft and mastoid, (2) a rapidly growing polypoid mass that was visible in the middle ear and external auditory canal, and (3) seventh nerve involvement and destruction of bone. Definitive treatment with the use of systemic chemotherapy and radiation therapy to the invaded structures was followed by maintenance chemotherapy for up to 24 months. Surgical treatment was sufficient to obtain adequate biopsy material. All patients recovered variable degrees of motor nerve functions. One patient experienced a meningococcal meningitis years after treatment; this condition resulted in total deafness. The results suggest that multiple-drug chemotherapy and radiation therapy for all involved areas are the mainstay of treatment for this disease entity.

(Arch Otolaryngol 105:310-313, 1979)

Author Affiliations
From the Departments of Surgery (Dr Goepfert), Pediatrics (Dr Cangir), Radiotherapy (Dr Lindberg), and Pathology (Dr Ayala), University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute, Houston, and the Division of Otolaryngology, Program in Surgery, University of Texas Health Science Center, Houston (Dr Goepfert).

Footnotes
Accepted for publication Feb 11, 1978.

Reprint requests to M. D. Anderson Hospital and Tumor Institute, 6723 Bertner Dr, Houston, TX 77030 (Dr Goepfert).

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